Strong customized treatments with combinable transdermic ingredients to solve up to three individual problems simultaneously

Worldwide Innovation

Highly-effective ingredients for the most felt and wide-spread dermo-cosmetic problems.
Auxiliary actives developed to further support the 10 Strong Ingredients
Formulated to optimize the penetration capacity of the X-Ingredients Actives

X-Ingredients is an innovative concept of customizable dermo-cosmetic preparations that is based on each user being able to easily select their own highly effective Transdermic Technology active ingredients (Strong Ingredients) for targeting specific skin problems or conditions (Strong Problems) and mix them with the transdermic base cream at the point of use.

Existing cosmetic products in the skincare market may not adequately respond to the general conditions of the consumer’s skin or to more specific individual problems affecting their skin and, above all, the cosmetic action developed by a single product is not usually able to solve a range of skin concerns.

There is a growing demand for finding simple but effective personalized solutions to strong problems, that is to say each user’s specific skin problems. Individual skin problems, which vary in origin and nature, and may also occur at the same time, are addressed using solutions formulated with X-Ingredients bespoke recipes.

The consumer is able to select strong, highly effective solutions, which combines to create a unique, original and highly personalized treatment for use at home.

Customization and extraordinary efficacy

The concentrated actives consist in 10 Strong Ingredients and 5 Extra Help which provide auxiliary actions. These ingredients can be combined in various ways: first choose the answer to the main skin problem and then choose the solution to additional or related skin conditions. Up to three X-Ingredients (among Strong Ingredients and Extra Help) can be combined. All the active molecules are highly concentrated and boosted thorugh the Labo Transdermic Technology enhancers for a controlled penetration in the cutaneous layers.

The Choice

By referring to the summary table here aside, the skin conditions requiring treatment are easily identifiable, even for non-pros, also thanks to dedicated recommendation form available for clarity of choice.

How to use

Just add one to three drops of the concentrated active X-Ingredient to the selected  base cream at the point of use. Up to three concentrated active ingredients can be used together for differentiated problems. The X-Ingredients are contained in 10 ml droppers.

Transdermic Bases

There are three bases for the face (available in a 40 ml airless dispenser) and one for the eyes-lips (available in a 15 ml airless dispenser). These have specific textures and enhancer ingredients to optimise the transdermic penetration of the active molecules. The packaging for each base cream also contains a small dish and a little spatula for easily blending the emulsion with the drops of the selected ingredients.

Perfume free (X-Ingredients, Base E) • Allergens Free Perfumes (Bases R/L/O) • Paraben Free • Free of Colorants (Except for X-Ingredients 8) • Silicone Free • Mineral Oils Free • Nickel Tested Dermotologically Tested

Labo has many years of experience developing research into the skin’s physiology, as well as the most effective active ingredients that are able to penetrate the skin. The result is our patented Transdermic Technology (Swiss patent no. CH 711 466), which allows to control the capability of each individual dermo-cosmetic molecules to penetrate the skin layers (epidermis and dermis). Once absorbed, these active ingredients are able to develop a significant dermo-cosmetic activity that is capable of providing guaranteed solutions for the main skin problems.

Transdermic Technology is based on the very low molecular weight of the active molecules, enabling them to penetrate through the skin’s different layers. It is precisely this characteristic that makes them very effective actives.

Transdermic penetration control and optimization are also possible thanks to the presence of 3 enhancers (Caprylyl Glycol, Decylene Glycol and Pentylene Glycol).

The percentages reported on the packaging refer to the transdermic penetration of the functional active molecules, in solution, after 24 hours. Transdermic penetration was made possible by the new Labo technology and tested by means of Franz Cells.

All X-Ingredients Bases come in a box containing also a small dish and a little spatula that have been specifically conceived to mix the base with the drops of X-Ingredients concentrated actives.

The recommended quantity of face cream per application is two doses. Dispense the two doses (to be chosen among bases R, L or O) on the small dish. The number of concentrated actives’ drops to be added depends on the number of X-Ingredients droppers chosen.

For example, when combining one X-Ingredients dropper, it is possible to add three drops to the base cream.

When combining two droppers, it is possible to add three drops per bottle, for a total of six drops.

When combining three X-Ingredients, the recommended number of drops per bottle is two, for a total of six drops.

By means of the little spatula, mix the ingredients up to forming a fluid and perfectly blended preparation, then apply it on face and neck after a thorough cleansing. Use once or twice a day for a 4-week treatment.

The recommended doses for Base E (eyes and lips) consist in one dose of cream and one drop of X-Ingredients dropper, up to a maximum of two X-Ingredients actives.


If I have only one problem I care (only one Strong Problem), how many drops of X-Ingredients active may I use?

If you use only one X-Ingredients, Labo recommends to use 3 drops.

Can I apply the Base + X-Ingredients (1 or more) more times per day (ex: morning and evening)?

Sure. You can use the same base both morning and evening, or you can choose a lighter base for the morning (Light Base), and a more nourishing one for the evening (Rich Base).

Can I use X-Ingredients actives on the face and then apply the cream?

No. The drops must be always blended with the base cream since the presence of the 3 Enhancers in the cream help the active ingredients to penetrate the different skin’s layers.

Can I spread on the face more X-Ingredients actives together?

No. Since the concentrations of the X-Ingredients actives are higher, these must be blended to the base cream before the application on the skin.

What happens if I use more than 3 drops for each X-Ingredients? And what about if I use less?

No negative consequences. But, in order to avoid under- or overdoses it is better to follow Labo instructions.

How long a treatment should last?

The treatment lasts 4 weeks but it can be repeated more times during the year and can become a daily skincare routine.

Can I add the X-Ingredients actives to a cream different than the Transdermic Bases included in the line?

Labo doesn’t recommend the use of a different cream due to the product effectiveness: the bases of X-Ingredients contain the Transdermic Technology to help the penetration of the added active ingredients and therefore to boost the product efficacy. On the contrary, other creams can be used with the Extra-Help products since they contain cross-linked ingredients and their combinations can be manifold.

Are there any conflicts, interactions or contraindications in the combined use of the X-Ingredients?

No, none.

If I use more than 3 drops of an X-Ingredients, can we have an overdosage?

No if this occurs by chance, clearly it is better if this is not repeated daily.

How choose the right base (R, L, O)?

The choice of the base is made according to the skin type, but also for desired comfort (more or less emollient cream) or for seasonality (hot, humid, dry climate, etc.)

If I choose 3 different X-Ingredients actives, how can I mix with the base (R, L, O) in the best possible way?

The dosage suggested by Labo in this specific case foresees 2 drops for each X-Ingredients, for a total amount of 6 drops.

How the concentrations of the X-Ingredients actives have been developed?

The concentrations of the active ingredients of X-Ingredients are 3 to 10 times higher than the concentrations normally used / recommended in the products available on the market. This number varies according to the active ingredient that is considered, for example 3 for Growth Factors, 10 for Collagen, Elastin, amino acids. We also use a multiplicative coefficient of 5.7 to take into account the dilution that the X-Ingredients undergoes when added to the base cream.

Are there any combinations that should be avoided when using base creams as a day emulsion?

No. But, in case of use of Vitamin A and Glycolic Acid, the sun exposure is not recommended during the treatment.

Which are the X-Ingredients recommended to be used exclusively in the evening?

It is better to use Vitamin A during the evening.

How combine the use of a sunfilter and the X-Ingredients treatment?

The sun filter (it is recommended LTD Fluid Base SPF50+) should be applied over the Transdermic Base enriched with X-Ingredients or Extra Help and never mixed during the preparation.