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Crescina Hair Follicular Islands
Crescina Hair Follicular Islands
Crescina

Crescina

Patent

Crescina Transdermic HFSC Hair Follicular Islands

  • It helps promote the physiological hair growth
  • For thinning hair
  • Defends the follicular islands from the damage of thinning hair
Crescina Hair Follicular Islands
Crescina Hair Follicular Islands

Crescina Transdermic HFSC Hair Follicular Islands is a cosmetic treatment in vials for topical use. This new formulation takes care of each anatomical and functional structure of the Hair Follicular Island, and supplies the adequate energy for the needs of the island, thus providing a greater impulse to the physiological hair growth.

It contains the Re-Growth, HFSC, Follicular Islands and Booster Complexes with Transdermic Technology that allows the ingredients to penetrate through the follicular opening and through the whole scalp.

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A SPECIFIC ANSWER TO THE THINNING PROBLEM

A concentrate of innovation dedicated to both single hair follicles and hair follicular islands

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EFFECTIVE IN 100% OF THE SUBJECTS TESTED*

From +7 to +41 new hairs growing in 1.8 cm².**

*Result after 4 months of in vivo clinical/instrumental double-blind testing, randomized and controlled with a placebo on 46 subjects (23 treated with Crescina HFSC and 23 with the placebo). The male subjects presented levels of thinning at grades II, III, III vertex and IV of the Hamilton-Norwood scale.

**All of the subjects recorded positive results from a minimum of +7 to a maximum of +41 new hairs growing in an area subject to an electronic count of 1.8 cm². The results of the test are statistically significant.

HOW TO FIND THE MOST SUITABLE TREATMENT?

Check the table to know your stage of thinning and find the dosage that best suits your needs.

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THINNING SCALE - WOMAN

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THINNING SCALE - MAN

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3 USEFUL TIPS

  1. Use Crescina Transdermic HFSC Hair Follicular Islands vials twice a year, for at least 2 consecutive months (4 months recommended).

  2. Keep your head leaned backwards while applying the product and be careful not to let it drip on the face.

  3. In the absence of excess sebum, wash your hair at your usual frequency.

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HOW TO USE THE VIAL

Apply one vial a day for 5 consecutive days on dry hair and follow with a two-day break. Do not rinse.
FOR EXTERNAL USE ONLY. DO NOT INJECT. DO NOT SWALLOW.

Illustrazione 1

1. Take the special rigid plastic vial breaker from its holder in the pack.

Illustrazione 2

2. Fit the vial breaker to the vial, simply positioning it over the neck. Grip the vial breaker between finger and thumb and snap off the top part of the vial, applying light but firm pressure.

Illustrazione 3

3. Take the applicator nozzle from its holder.

Illustrazione 4

4. Fit the applicator onto the neck of the opened vial.

Illustrazione 5

5. Remove the cap from the applicator.

Illustrazione 6

6. Apply the preparation to a dry and clean scalp, line by line, concentrating on the areas where thinning is most noticeable. Massage gently to help its penetration.

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Description and ingredients

CRESCINA TRANSDERMIC HFSC HAIR FOLLICULAR ISLANDS

Crescina Transdermic HFSC Hair Follicular Islands includes the core of Crescina Re-Growth (Cysteine, Lysine, Glycoprotein), which helps promote the physiological hair growth. A part of the active ingredients (Cysteine, Lysine, Glycoprotein and Stem-Engine – HFSC* formula) is inserted within specific ciclodextrins that allow its gradual, ongoing release. Contains the special Swiss patent complex for the Hair Follicular Islands (Glycogen, Glutamyl-amido-ethyl-indole, Lupinus albus, Proline, Triticum vulgare Extract + Glycine max + Scutellaria baicalensis) to help the hair bulbs, singular or specifically associated to hair follicular islands, to help their growth and development.

The Patented Transdermic Technology (Swiss Patent CH 711 466) allows the active substances of Re-Growth, HFSC, Hair Follicular Islands and Booster Complexes to penetrate through the hair system not only via trans-follicular route (follicle opening) but also transdermally (ex vivo test with Franz Cells) through the scalp skin layers (epidermis and dermis). Thanks to their low molecular weight and to the presence of 3 enhancers (Pentylene Glycol, Declylene Glycol, Caprylil Glycol), the functional active ingredients are facilitated in their penetration and in their performance.

Recommended in cases of thinning due to physiological – not pathological – causes. Does not act on completely atrophied follicles.

INCI

Crescina Transdermic HFSC Hair Follicular Islands 1900 Man
Alcohol Denat., Aqua, Glycerin, Pentylene Glycol, Caprylyl Glycol, Proline, Butylene Glycol, Glycine, Methionine, Propanediol, Lysine HCl, Benzyl Nicotinate, Acetyl Cysteine, Decylene Glycol, Benzophenone-4, Glycogen, Laminaria Digitata Extract, Hydrolyzed Lupine Protein, Glycyrrhetinic Acid, Menthol, Silanediol Salicylate, Hydroxypropyl Cyclodextrin, Triethanolamine, Threonine, Serine, Arginine, Lactic Acid, Hydrolyzed Pea, Allantoin, Glycine Soja Germ Extract, Triticum Vulgare Germ Extract, Adenosine, Propylene Glycol, Zinc Acetylmethionate, Hydrolyzed Rice Protein, Hematite Extract, Phosphatidylcholine, Hydrolyzed Soy Protein, Gluconolactone, Scutellaria Baicalensis Root Extract, Sodium Benzoate, Glycoproteins, Hydrolyzed DNA, Hydrolyzed RNA, Salicylic Acid, Pentapeptide-31, Sodium Succinate, Eriobotrya Japonica Leaf Extract, Glutamylamidoethyl Indole, Glycine Soja (Soybean) Oil, Sodium Oleate, Glutamic Acid, Ethylhexylglycerin, Copper Tripeptide-1, Hydrogenated Lecithin, Artemia Extract, Valine, Calcium Gluconate, Sodium Metabisulfite, Sorbic Acid, Trisodium EDTA, Potassium Sorbate, Sodium Hydroxide, Phenoxyethanol, Disodium EDTA, CI 19140, CI 16255, CI 28440, CI 14720, CI 73015.

Crescina Transdermic HFSC Hair Follicular Islands 1900 Woman
Alcohol Denat., Aqua, Glycerin, Pentylene Glycol, Caprylyl Glycol, Proline, Butylene Glycol, Glycine, Methionine, Propanediol, Benzyl Nicotinate, Decylene Glycol, Lysine HCl, Acetyl Cysteine, Benzophenone-4, Glycogen, Laminaria Digitata Extract, Hydrolyzed Lupine Protein, Glycyrrhetinic Acid, Menthol, Silanediol Salicylate, Glutamine, Triethanolamine, Hydroxypropyl Cyclodextrin, Threonine, Serine, Arginine, Lactic Acid, Polyquaternium-68, Hydrolyzed Pea, Allantoin, Biotin, Glycine Soja Germ Extract, Triticum Vulgare Germ Extract, Adenosine, Propylene Glycol, Zinc Acetylmethionate, Hydrolyzed Rice Protein, Hematite Extract, Phosphatidylcholine, Hydrolyzed Soy Protein, Gluconolactone, Scutellaria Baicalensis Root Extract, Glycoproteins, Pueraria Mirifica Root Extract, Hydrolyzed DNA, Hydrolyzed RNA, Pentapeptide-31, Salicylic Acid, Copper Tripeptide-1, Sodium Succinate, Eriobotrya Japonica Leaf Extract, Glutamylamidoethyl Indole, Ethylhexylglycerin, Glycine Soja (Soybean) Oil, Sodium Oleate, Glutamic Acid, Hydrogenated Lecithin, Artemia Extract, Valine, Calcium Gluconate, Sodium Metabisulfite, Sorbic Acid, Sodium Benzoate, Potassium Sorbate, Sodium Hydroxide, Phenoxyethanol, Disodium EDTA, Trisodium EDTA, CI 19140, CI 16255, CI 28440, CI 14720, CI 73015

The active ingredients of Labo products may be subject to possible modifications. For an updated version, before using the product, read the list of ingredients on the package.

Technology

Labo Cosprophar has been conducting research on hair follicular islands since 2002. After the first patent (2003) and other innovations in its formulas, in 2015 the researchers defined a formula (Swiss patent 693 816 A5) that cares for every anatomic and functional structure of the hair follicular island, providing an appropriate source of energy to meet the needs of the hair follicular island (which are greater than the needs of the single hair follicle). The components of the hair follicular islands have an overall effect on the hair follicular island, stimulating cell activity in the hair bulbs and follicles and offering a boost for physiological hair growth. The same active ingredients also have positive properties for single hair follicles, for both healthy and thinning hair.

The Patented Transdermic Technology (Swiss Patent CH 711 466) allows the active substances of Re-Growth, HFSC, Hair Follicular Islands and Booster Complexes to penetrate through the hair system not only via trans-follicular route (follicle opening) but also transdermally (ex vivo test with Franz Cells) through the scalp skin layers (epidermis and dermis). Thanks to their low molecular weight and to the presence of 3 enhancers (Pentylene Glycol, Declylene Glycol, Caprylil Glycol), the functional active ingredients are facilitated in their penetration and in their performance.

Effectiveness

CRESCINA EFFICACY TESTS

Labo carries out several clinical and instrumental tests that prove the effectiveness and safety of its treatments.

Below is a summary of some of the most recent tests carried out on Crescina treatments.

86% of the consumers claim they had hair regrowth results in thinned areas thanks to Crescina treatment

85.8% of the consumers claim they noticed an increase in hair thickness thanks to Crescina treatment

Self-assessment test – 8,243 consumers, technical-statistical data processing conducted by Praxidia.

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93% of the consumers evaluated positively their overall satisfaction after using Crescina treatment.

88% of the consumers evaluated positively their new hair growth after using Crescina treatment.

90% of the testers judged positively Crescina treatment in relation to the amount of hair.

Self-assessment test – 50 women from AlFemminile community, 2 months of daily use of Crescina Transdermic Re-Growth

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+11.5% of hair in anagen phase, after 2 months

+18.3% of hair in anagen phase, after 4 months

-18.6% of hair in telogen phase, after 2 months

-29.17% of hair in telogen phase, after 4 months

Phototrichogram – 46 women, 2/4 months of Crescina HFSC daily use

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-28% of lost hairs, after 2 months

-43% of lost hairs, after 4 months

95% of the subjects improved after 2 months

100% of the subjects improved after 4 months

Pull test – 42 volunteers, 2/4 months of Crescina HFSC daily use

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65.2% of the consumers gave a positive opinion about the regrowth of new hair

60.9% of them gave a positive opinion about the increased rate in hair growth

73.9% of them gave a positive opinion about the increase in hair thickness

82.6% of them gave a positive opinion about the increased strength of their hair

82.6% of them gave a positive opinion about the reduction in hair loss

Self-assessment test – 46 volunteers, 2/4 months of Crescina HFSC daily use

—–

91.3% of the consumers are satisfied with hair growth results

88.7% of the consumers are satisfied with hair thickness increase

Self-assessment test – 230 consumers, 2/4 months of Crescina HFSC use

How to use

HOW TO USE

1. Take the special rigid plastic vial breaker from its holder in the pack.

2. Fit the vial breaker to the vial, simply positioning it over the neck. Grip the vial breaker between finger and thumb and snap off the top part of the vial, applying light but firm pressure.

3. Take the applicator nozzle from its holder.

4. Fit the applicator onto the neck of the opened vial.

5. Remove the cap from the applicator.

6. Apply the preparation to a dry and clean scalp, line by line, concentrating on the areas where thinning is most noticeable. Massage gently to help its penetration.

Crescina Transdermic HFSC Hair Follicular Islands (Re-Growth) vials contain 3,5 ml of the preparation and are suitable for a daily use during the first 5 days of the week, followed by a 2-day break.. The product is available in boxes of 20 vials (for a 1-month treatment) and 40 vials (for a 2-month treatment). A minimum treatment of 2 months is recommended.

Warnings: For external use only. Do not inject. Do not swallow. Avoid the contact with eyes or mucous membranes.

Patents

SWISS PATENT CH 703 390

Trichological lotion for topical use activating the hair follicle stem cells to stimulate the physiological hair growth.

SWISS PATENT CH 693 814

Trichological lotion for topical use to stimulate the hair growth and to increase the hair shaft thickness.

SWISS PATENT CH 693 815

Trichological lotion for topical use to stimulate the hair growth with extended action.

SWISS PATENT CH 697 229

Trichological lotion for topical use activating the hair follicle stem cells to stimulate the physiological hair growth.

SWISS PATENT CH 693 816

Trichological lotion for topical use to stimulate the hair growth and the treatment of follicular islands.

SWISS PATENT CH 711 466

Dermo-cosmetic product for topical application with penetration enhancing properties and process for its production.

Frequent questions

Can I use Crescina treatment during pregnancy/breastfeeding?

Crescina can be used during pregnancy/breastfeeding. However, because of the peculiarities of this particular physiological condition, Labo usually recommends to inform your doctor about the treatment application.

Can I dye my hair during the treatment?

In order not to stress too much the scalp, it is advisable to suspend the treatment when you dye your hair and to resume the application from the day after.

Is Crescina treatment compatible with other hair products like conditioner or hair spry?

Sure, there are no incompatibilities at all.

Do I need to buy a shampoo of the same products?

It is not essential to buy a shampoo of the same line. It is important, however, to use a mild shampoo: from this point of view, Crescina shampoo guarantees the maximum quality.

How long does the treatment last?

The minimum period of application is 2 months, although it is usually recommended to apply the treatment for at least 3/4 months.

Is it normal to feel a slight itching sensation once the product has been applied on the scalp?

Absolutely yes. The preparation contains a mild vasodilator that may cause a slight heat reaction with reddening of the skin for a short time.

How old should I be to start using Crescina?

Considering the hydroalcoholic-based formula of the treatment and the presence of a topical vasodilator that can cause a slight reddening on the skin, for prudential purposes we would recommend the use of Crescina only since legal age.

How do I apply Crescina Treatment?

Crescina should be applied on dry and clean hair (in the morning or evening, depending on your preference) and left to act until the next washing, preferably recommended not earlier than 24 hours since the application.

Where can I find more information regarding the effectiveness of Crescina?

Crescina makes use of numerous tests. Springer’s authoritative journal “Dermatology and Therapy” has published a study that the researchers of Pavia University Department of Biology and Biotechnologies carried out on Crescina HFSC. The study is available on Open Access.

How soon, after the star of Crescina treatment application, results will begin to be visible?

Results depend on the individual conditions. According to the test published in "Dermatology and Therapy", 95.7% of the subjects obtained positive results in terms of new hair growth after 2 months of treatment, 100% of the subjects obtains results in terms of new hair growth after 4 months of treatment.

Why does Crescina preparation not report the expiry date on the packaging?

The PaO (Period After Opening) symbol must be reported on the labelling of all cosmetic products, except for those having a minimum durability of less than 30 months, that will therefore report the caption “Best before…”; single-dose products (such as Crescina vials).

How to choose between Crescina Re-Growth and Crescina Hair Follicular Islands?

Crescina Re-Growth is suitable for those people with thinning hair problems, and in particular for those approaching the Treatment for the first time. Crescina Hair Follicular Islands, instead, is normally recommended for those people who already used Crescina, for a greater activity on the Follicular Islands and not only on the single hair follicles. Crescina Re-Growth is also recommended for the maintenance (1 or 2 vials per week after the 2-month cycle) while Crescina Hair Follicular Islands is a treatment for those who are more inclined to news and scientific discovery.

What are the differences between Crescina vials for women and for men?

Crescina Man and Woman preparations differ since the formulas are specifically designed for the hair characteristics of the two sexes. For example, men's vials contain a lower quantity of emollient substances as their hair is usually oilier than women's hair, who, on the other hand - by virtue of straighteners, hairdryers and dyes - have drier hair. It is therefore preferable that men use men's vials, while women use women’s vials, although, as you can easily imagine, there is no harm in case of reverse use.

Are Crescina preparations always effective?

The essential condition for Crescina preparations to act effectively is that the bulbs inside the hair follicles are not completely atrophied. Thinning must be caused by physiological and non-pathological causes, such as cicatricial alopecia, alopecia areata, etc. In addition, the product must be used for a period of not less than 2 months.

Crescina preparations contain a mild topical vasodilator. Is it possible that the application of Crescina causes an alteration in blood pressure?

Absolutely not. Crescina is a cosmetic product and does not enter the circulation but performs an external localized action. The topical vasodilator is useful for reactivating the superficial microcirculation in the scalp.

Does Crescina weigh hair down?

No, as it contains a hydroalcoholic base that dries quickly and leaves the hair not greasy nor heavy.

Do I always have to wash my hair before applying Crescina?

We suggest to apply the preparation on a clean and dry scalp in order to facilitate the penetration of the active ingredients. However, it is not necessary to wash your hair every day, unless the scalp is particularly oily or with dandruff.

Does the treatment also affect atrophied follicles?

The Crescina treatment can act on dormant but not completely atrophied follicles.
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