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Collagenina

Collagenina

Patent

Collagenina
Face Pack with 6 Collagens

  • Replenishes and firms the skin tissues of the neck
  • With 6 Collagens with different molecular weights for fast penetration to best contrast skin sagging
  • With Transdermic Technology for better in-depth penetration of the Collagens
  • Daily or continuation treatment of the 14-day Face Pack with 6 Collagens

Collagenina is a plumping and firming dermal treatment for at-home use.

Inspired by the Transdermic Technology patented by Labo, Collagenina Face Pack helps plump up and firm the skin tissues of the face characterized by relaxation. With 6 Collagens with different molecular weights, its formula includes endogenous collagen components to stimulate the internal production of collagen and active ingredients to prepare the skin for a higher penetration of collagens and to continue to provide collagen throughout the day.

Effectiveness of Collagenina: Collagenina Face Pack with 6 Collagens, for at-home use, is effective in just 14 days.
Thanks to its properties, it is able to significantly increase the density of skin tissues and the thickness of epidermis and dermis (in vivo instrumental test by ultrasound).

It contains 14 doses of Preparatory Gel + 14 doses of Plumping Firming Face Pack + 14 doses of Emulsion + 2 Graduated Dispensers + 1 Spatula.

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PLUMPING FIRMING EFFECT

THE SECRET OF OUR SKIN? COLLAGEN.

These are the 6 fast penetrating Collagens included in the powerful formulation of Collagenina, the treatment for at-home use that targets skin relaxation to bring new density to the skin of the face.


PLUMPING FIRMING FACE PACK WITH TRANSDERMIC TECHNOLOGY.

Collagenina's unique formula features 6 fast penetrating Collagens with different molecular weights that, thanks to the Transdermic Technology patented by Labo, are able to penetrate in depth into the skin layers with tested efficacy to firm and plump up the loose and marked tissues

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TESTED EFFICACY OF COLLAGENINA

SKIN DENSITY 100% subjects improved
SKIN THICKNESS 100% subjects improved
REMODELING EFFECT 91.7% subjects improved

*Clinical study carried out on 20 female subjects, aged 35 to 60 years old, with skin sagging/ptosis of the lower part of the face, marked micro-relief and micro-wrinkles. Evaluation after 14 days of use.



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EFFECTIVE IN 14 DAYS

YOUR ALLY AGAINST SKIN LAXITY

Collagen is the main structural protein of the skin, comparable to the frame of a mattress. The reduction of collagen results in sagging, causing the relaxation of the skin tissues, which thus lose firmness and thickness. This is particularly noticeable on the face where the features appear visibly tired and marked and the skin looks floppy. Thanks to Collagenina you can regain a plumped and firmed facial skin in just 14 days.


3 USEFUL TIPS

  1. Carry out the treatment in the evening on perfectly cleansed skin.

  2. Repeat the treatment several times a year.

  3. Between intensive treatments, use the daily cream treatments from Collagenina range.

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APPLYING COLLAGENINA IS EASY

Collagenina Treatment shall be applied daily for 14 days, preferably in the evening, on perfectly cleansed skin. All it takes is 12 minutes.

collagenina_step1

Draw up 2 ml with the help of the appropriate dispenser and distribute it all over the face avoiding the periocular area and mucous membranes.

collagenina_step2

Leave to act for 2 minutes. Close the bottle with the rubber cap provided in the box.

collagenina_step3

Take a small amount of pack from the jar with the help of the spatula and spread a thin layer of it on the face: cheeks, jaw line, forehead. Avoid the eye area and the nose.

collagenina_step4

Wait for 10 minutes, then remove the residue with the spatula.

collagenina_step5

Rinse with warm water, using, if necessary, a sponge or a microfiber cloth. Pat dry.

collagenina_step6

Draw up 2 ml of Emulsion with 6 Collagens with the appropriate doser, and spread the preparation on the treated areas.


DISCOVER THE BEST ROUTINE

  1. Start off by using the intensive treatment.

    Collagenina Treatment

    Collagenina
    Face Pack with 6 Collagens

  2. Coadjutate the effect of the intensive treatment with the Day Cream and Night Cream from the range.

    Collagenina
    Day Cream with 6 Collagens

  3. Use the daily treatment specifically for the neck.

    Collagenina
    Neck Cream with 6 Collagens

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Description and ingredients

COLLAGENINA FACE PACK WITH 6 COLLAGENS
INTENSIVE TREATMENT

Collagenina is a plumping and firming dermal treatment for at-home use.

Collagenina Face Pack helps to plump up and firm the skin tissues of the face characterized by relaxation. With 6 Collagens with different molecular weights, its formula includes endogenous collagen components to stimulate the internal production of collagen and actives to prepare the skin for a higher penetration of collagens and to continue to provide collagen throughout the day.

Inspired by the Transdermic Technology patented by Labo, Collagenina is a treatment with 6 collagens for in-depth fast penetration consisting of:

14 Doses of Penetration Preparatory Gel
14 Doses of Plumping Firming Face Pack with 6 Collagens
14 Doses of Emulsion with 6 Collagens
2 graduated dispensers
1 Spatula

INCI

Collagenina Face Pack with 6 Collagens - Grade 2
Aqua, Ceteareth-30, Glycerin, Ceteareth-20, PEG-7 Glyceryl Cocoate, Hydrolyzed Collagen, Soluble Collagen, Caprylic/Capric Triglyceride, Betaine, PPG-3 Caprylyl Ether, Phenoxyethanol, Silica Dimethyl Silylate, Caprylyl Glycol, Xanthan Gum, Prunus Amygdalus Dulcis Oil, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Parfum, Butylene Glycol, Pentylene Glycol, Decylene Glycol, Propylene Glycol, Limonene, Leuconostoc/Radish Root Ferment Filtrate, Sodium Ascorbyl Phosphate, Ethylhexylglycerin, Alcohol, Disodium EDTA, BHT, Collagen Amino Acids, Sodium Hydroxide, Glycine, Proline, Hydroxyproline, Phospholipids, Linalool, Carnosine, Biosaccharide Gum-1, Palmitoyl Tripeptide-5, CI 19140, Sodium Benzoate, CI 16255, Tocopherol, CI 18050, CI 28440, CI 14720, Silybum Marianum Fruit Extract, CI 73015.

Collagenina Preparatory Gel - Grade 2
Aqua, Propylene Glycol, Arginine, Pyrus Malus Fruit Extract, Tartaric Acid, Citric Acid, Citrus Limon Fruit Extract, Hydrolyzed Grape Fruit, Hydrolyzed Wheat Bran, Phenoxyethanol, Glycerin, Maltodextrin, Xanthan Gum, Butylene Glycol, Caprylyl Glycol, Decylene Glycol, Pentylene Glycol, Ethylhexylglycerin, Sodium Benzoate, Potassium Sorbate, Vaccinium Myrtillus Fruit Extract, Benzyl Alcohol, Protease.

Collagenina Emulsion with 6 Collagens - Grade 2
Aqua, Cetearyl Isononanoate, Glyceryl Stearate SE, Ethylhexyl Cocoate, Decyl Oleate, Ceteareth-20, Soluble Collagen, Hydrolyzed Collagen, Cetyl Alcohol, Aluminum Starch Octenylsuccinate, Glyceryl Stearate, Phenoxyethanol, Caprylyl Glycol, Cocos Nucifera Oil, Ethylhexylglycerin, Xylitol, Parfum, Carbomer, Tocopheryl Acetate, Glycerin, Butylene Glycol, Decylene Glycol, Pentylene Glycol, Propylene Glycol, Leuconostoc/Radish Root Ferment Filtrate, Sodium Ascorbyl Phosphate, BHT, Alcohol, Collagen Amino Acids, Glycine, Proline, Hydroxyproline, Palmitoyl Tripeptide-5, Tocopherol, Silybum Marianum Fruit Extract, Carnosine, Sodium Benzoate, CI 19140, CI 14700, Limonene, Linalool, Lecithin, Geraniol, Coumarin, Eugenol, CI 42090.

The various dosages of the preparation, in addition to having different percentages of actives, may also include variations with regard to ingredients. The information reported here refers to a specific preparation, for the ingredient list of other dosages we invite you to refer to what is written on the packaging.

The ingredients of Labo Suisse products may be subject to periodic updates.
For an updated version, please read the ingredient list on the packaging before using the product.

Technology

The skin is hardly permeable: to ensure that the functional molecules of the preparation penetrate the different skin layers, Labo researchers used the Transdermic Technology that lays on the low molecular weight of the active substances. This is the fundamental condition to guarantee their penetration exclusively in the skin layers, where they will play their real dermo-cosmetic effectiveness. The percentages here above refer to the transdermic penetration of the functional active molecules, in solution, after 24 hours, obtained with Labo Transdermic Technology and tested by means of Franz Cells.

PENETRATION TABLE OF THE ACTIVE INGREDIENTS - TEST CARRIED OUT BY MEANS OF FRANZ CELLS

6 COLLAGENS

Hydrolyzed Collagen 2K Da

101,3%

Collagen Amino Acids 2.4K Da

75,9%

Hydrolyzed Collagen 4K Da

66,5%

Hydrolyzed Collagen 12K Da

95,5%

Soluble Collagen 230K Da

90,5%

Soluble Collagen 300K Da

74,6%

OTHER ACTIVES

Glycine

75,9%

Proline

51,5%

Hydroxyproline

69,5%

Palmitoyl Tripeptide-5

91,1%

Effectiveness

CLINICAL-INSTRUMENTAL STUDY OF THE PLUMPING AND FIRMING EFFICACY OF A DERMAL-COSMETIC TREATMENT FOR FACE SKIN: COLLAGENINA FACE PACK WITH 6 COLLAGENS FOR IN-DEPTH FAST PENETRATION

The study aims to evaluate the efficacy of a cosmetic facial treatment in improving parameters related to skin aging such as skin ptosis, microrelief and micro-wrinkles. In order to reach this goal, a clinical study is carried out on 20 healthy female subjects, aged between 35 and 60 years old, showing sagging/ptosis of the lower part of the face (sagging jowls), marked microrelief and micro-wrinkles. Treatment efficacy is assessed after 7 and 14 days of products use by means of non-invasive image analysis. Moreover, at the end of the study, subjects are asked to express their opinion on tested treatment acceptability and efficacy by answering to a self-assessment questionnaire.

1) SKIN THICKNESS AND SKIN DENSITY (SKIN PLUMPNESS) WERE DETERMINED BY MEANS OF CHEEK ULTRASOUND.

The ultrasound allows to assess the echogenicity and to measure the skin thickness (epidermis + dermis). These parameters are related to the organization of the extracellular matrix (dermis) and are influenced by photoageing, chronoageing, and the water content of the skin. Skin thickness is measured in five points (white dotted lines) all over the analysed skin section; while echogenicity improvement is scored as an increase of the colours’ distribution inside the analysed skin section.

Skin Thickness Results

• +7.1% after 7 days and +14.9% after 14 days

• 95% of the subjects improved after 7 days

• 100% of the subjects improved after 14 days

Skin Density Results

• 8.9% after 7 days and +15.5% after 14 days

• 80% of the subjects improved after 7 days

• 100% of the subjects improved after 14 days

2) ASSESSMENT OF THE REMODELLING EFFECT ON FACE CONTOUR

The evaluation of the remodelling effect on the face contours is carried out by means of morphometric image analysis run out on the lateral digital photographic image of the face acquired before and after products use. A decrease of the measured distance indicates a remodelling.

Reshaping Effect Results

• -0.63 mm after 7 days and -1.15 mm after 14 days

• 85% of the subjects improved after 7 days

• 91.7% of the subjects improved after 14 days

3) SKIN PROFILOMETRY

Skin surface is quantitatively assessed by Primos 3D (GFMesstechnik GmbH). Primos 3D is a non-contact in vivo skin measurement device based on structured light projection. In conjunction with a comprehensive 3-D measurement and evaluation software, the sensor allows to evaluate skin surface properties (i.e. wrinkle depth, volume, skin roughness, etc.). In this study Sa parameter (skin profilometry) is calculated on the cheek.

Skin profilometry results

• -5.4% after 7 days and -9.8% after 14 days

• 90% of the subjects improved after 7 days

• 100% of the subjects improved after 14 days

Collagenina treatment self-assessment test

At the end of the study, subjects are asked to express their opinion on the tested product by replying to a self-assessment questionnaire. For the self-assessments, judgment is expressed as “Yes” / “No”.

Does the treatment improve skin firmness? YES 95% – NO 5%

Does the treatment reduce the sagging skin on the face? YES 85% – NO 15%

Does the treatment reduce the visibility of wrinkles? YES 85% – NO 15%

Does the treatment improve skin smoothness? YES 95% – NO 5%

Are you satisfied with the effect obtained using the products? YES 90% – NO 10%

Would you recommend the use of the products for their characteristics? YES 90% – NO 10%

Finally, the product has been judged positively by most subjects (≥85%) for all investigated aspects related to efficacy: skin firmness, visibility of wrinkles, skin smoothness, facial skin relaxation.

How to use

HOW TO USE

1. Draw up 2 ml of Preparatory Gel with the help of the appropriate dispenser. Distribute it all over the face avoiding the periocular area and mucous membranes.
2. Leave to act for 2 minutes. Close the bottle with the rubber cap provided in the box.
3. Take a small amount of pack from the jar with the help of the spatula and spread a thin layer of it on the face: cheeks, jaw line, forehead. Avoid the eye area and the nose.
4. Wait for 10 minutes, then remove the residue with the spatula.
5. Rinse with warm water, using, if necessary, a sponge or a microfiber cloth. Pat dry.
6. Draw up 2 ml of Emulsion with 6 Collagens with the appropriate doser, and spread the preparation on the treated areas.

Warnings: Dermo-cosmetic preparations. External use only. Avoid direct contact with the eyes. Do not inject. Do not swallow. Keep out of the reach of children. Keep away from light and heat.

Patents

SWISS PATENT CH 711 466

Dermo-cosmetic composition for topical application with penetration enhancing properties and procedure for its production.

Frequent questions

When should I use Collagenina?

Collagenina Face Pack with 6 Collagens is a plumping firming dermal treatment indicated for the skin tissues of the face characterized by relaxation, tired and drooping features, marked microrelief. It can be used any time of the year, and does not cause photosensitization reactions.

How do I prep the skin for Collagenina Intensive Treatment?

As it is a preparation that features the Transdermic Technology, good cleansing, both daily and periodically, is recommended in order to get the maximum efficacy results from its formulation properties. Cleansing should be carried out according to skin type and habits (which can affect skin quality).

Should Collagenina Intensive Treatment be carried out only in the evening?

The treatment should preferably be carried out in the evening, on perfectly cleansed skin. However, there are no contraindications in using the Intensive Treatment in the morning instead of in the evening. In the case of using the Intensive Treatment with Collagenina Face Pack with 6 Collagens in the evening, Collagenina Day Cream can be used the morning after application. Vice versa, in the case of using the Intensive Treatment in the morning, Collagenina Night Cream can be used before bedtime. Collagenina daily cream treatments - Day Cream, Night Cream, Neck Cream - can also be used regardless of the Intensive Treatment, as they are daily treatments themselves.

Is it possible to apply makeup after the completion of Collagenina intensive treatment?

Absolutely. With the recommendation, however, to wait until the skin is well dried. The skin will look nicely smooth, velvety, radiant, and without residue.

Can Collagenina be used in combination with other dermo-cosmetic treatments?

In case you want to use your usual day or night creams (either from Labo or others) you can combine them as long as the Intensive Treatment with the application of Collagenina Face Pack is not overlaid with other products.
Collagenina treatment cycle recommended by Labo experts is about 1 month, i.e., the 14-day duration of the Face Pack plus two other weeks with the Daily Creams. It can be repeated several times a year or as needed.

How can I choose the grade of Collagenina?

Collagenina treatments are available with increasing concentrations of both the 6 Collagens for in-depth fast penetration and the additional molecules for the production of endogenous collagen. Concentrations correspond to three degrees of severity of skin relaxation: Grade 1 for initial laxity; Grade 2 for moderate laxity; Grade 3 for advanced laxity.